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Histone 3 antibody (H3K36me2)

The Mouse Monoclonal anti-Histone 3 antibody has been validated for WB, ChIP and DB. It is suitable to detect Histone 3 in samples from Human. There are 3+ publications available.
Catalog No. ABIN2668402

Quick Overview for Histone 3 antibody (H3K36me2) (ABIN2668402)

Target

See all Histone 3 (H3) Antibodies
Histone 3 (H3) (Histone H3 (H3))

Reactivity

  • 1621
  • 1118
  • 990
  • 39
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  • 1
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  • 1
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  • 1
Human

Host

  • 1412
  • 236
  • 8
  • 5
Mouse

Clonality

  • 1101
  • 559
  • 1
Monoclonal

Conjugate

  • 840
  • 102
  • 67
  • 67
  • 67
  • 67
  • 67
  • 67
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This Histone 3 antibody is un-conjugated

Application

  • 1273
  • 567
  • 486
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Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)

Clone

MABI 0332
  • Binding Specificity

    • 71
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    • 45
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    • 42
    • 38
    • 38
    • 36
    • 33
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    • 25
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    • 10
    H3K36me2

    Purification

    Protein G Chromatography

    Immunogen

    This Histone H3 dimethylLys36 antibody was raised against a peptide containing dimethylLys36 of human Histone H3.

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Concentration

    0.69 μg/μL

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Storage

    -20 °C

    Storage Comment

    Antibodies in solution can be stored at -20 °C for 2 years.

    Expiry Date

    6 months
  • Amendola, Zaghet, Ramalho, Vilstrup Johansen, Boxem, Salcini: "JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity." in: PLoS genetics, Vol. 13, Issue 2, pp. e1006632, (2017) (PubMed).

    García-Carpizo, Sarmentero, Han, Graña, Ruiz-Llorente, Pisano, Serrano, Brooks, Campbell, Barrero: "NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation." in: Scientific reports, Vol. 6, pp. 32952, (2016) (PubMed).

    Rechtsteiner, Ercan, Takasaki, Phippen, Egelhofer, Wang, Kimura, Lieb, Strome: "The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny." in: PLoS genetics, Vol. 6, Issue 9, pp. e1001091, (2010) (PubMed).

  • Target

    Histone 3 (H3) (Histone H3 (H3))

    Alternative Name

    Histone H3

    Molecular Weight

    17 kDa

    Gene ID

    3020
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